By Anthony H. Rose, D. W. Tempest
This quantity in a research-level sequence covers different elements of microbial body structure and biochemistry together with inositol metabolisms in yeasts, bacterial adhesion, natural acids, the bacterial flagellum and the mechanical behaviour of bacterial telephone partitions. it really is meant to be of use to microbiologists, biochemists and biotechnologists. different similar works during this sequence are volumes 29, 30 and 31.
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Additional resources for Advances in Microbial Physiology, Vol. 8
Cyclopropanc ftitty acids have been found in a variety of bacteria. The Gram-negative species include many members of the Enterobacteriaceae, including E . coli (Dauchy and Asselineau, 1960;Kaneshiro and Marr, 196l), A . , 1964) and the Brucellaceae, including Pasteurella pestis (Asselineau, 1961),Brucella abortus and B. Among the Gram-positive bacteria, cyclopropane fatty acids have been found in a number of the Lactobacillnceac, including Lactobacillus acidophilus, L. arabinosus, L . casei, L.
With the last preparation , arginylphosphatidylglycerol formation was also observed (Gould and Lennarz, 1967). Koostra and Smith ( 1969) demonstrated the formation of L-alanylphosphatidylglycerolby extracts of Mycoplusmu Eaidluwii from L-ala-t-RNA. Synthesis of Dalanylphosphatidylglycerol was also observed, but the mechanism of activation did not appear to require t-RNA. d. Information is lacking on the route of formation of phosphatidylinositol in the limited range of bacteria that synthesize this phospholipid or compounds containing it.
The formation of fatty acids in bacteria has been studied intensively in thc past decade in a number of laboratories. An outline of the biosyntliesis of saturated fatty acids is given in Fig. 7. This pathway begins with the formation of malonylCoA by carboxylation of acetyl-CoA in a manner analogous to the reaction found in animal systems (Wakil, 1958; Brady, 1958). Transfer of malonyl and acetyl residues to the free sulphydryl of an acyl carrier protein of molecular weight 9600 is carried out in E.